1、Creating a Vibrant Food Innovation Ecosystem:How Israel Is Advancing Alternative Proteins Across SectorsW H I T E P A P E RM A Y 2 0 2 4In collaboration with the Israel Innovation Authority,C4IR Israel and the Good Food Institute(GFI)IsraelImages:Getty ImagesDisclaimer This document is published by

2、the World Economic Forum as a contribution to a project,insight area or interaction.The findings,interpretations and conclusions expressed herein are a result of a collaborative process facilitated and endorsed by the World Economic Forum but whose results do not necessarily represent the views of t

3、he World Economic Forum,nor the entirety of its Members,Partners or other stakeholders.2024 World Economic Forum.All rights reserved.No part of this publication may be reproduced or transmitted in any form or by any means,including photocopying and recording,or by any information storage and retriev

4、al system.ContentsForeword 3Preface 4Executive summary 51 The role of governments in advancing alternative proteins 62 Understanding the present challenges in the field 93 Global acceleration of public support for alternative proteins 104 Case study:How Israel is advancing alternative proteins acros

5、s sectors 114.1 The Israeli alternative protein ecosystem today 114.2 Elevating alternative proteins as a national priority for sustainable growth 144.3 Government intervention points 164.4 A global perspective on the value chain 17Conclusion 18Contributors 20Endnotes 22Creating a Vibrant Food Innov

6、ation Ecosystem 2ForewordThe launch of this white paper comes at a critical moment for the climate agenda.With less than six years to go until 2030 to meet the commitments of the 2015 Paris Climate Agreement,leaders are at a crossroads,with finite choices before them that will determine the fate of

7、future generations and life on this planet.Among those choices is how best to transform food systems worldwide in a hot-and-getting-hotter world that looks set to be home to nearly 10 billion people by 2050.1 Increasingly,for some countries,the focus is on ensuring sustainable protein diversificatio

8、n pathways.The science is clear:it will be impossible for governments and others,including farmers,the private sector and consumers,to meet their obligations under the Paris Agreement2 and decarbonize the global economy without investing in sustainable protein diversification pathways and the overal

9、l food system.With global meat consumption projected to increase by at least 50%3 from 2012 levels by 2050,alternative proteins including plant-based and cultivated meat offer an additional globally scalable solution.These technologies serve as value-added agriculture compared to conventional produc

10、tion,have the potential to reduce emissions dramatically,feed more people with fewer resources,reduce public health risks and free up lands and waters worldwide for restoration and recovery.To underscore the critical role of country-led approaches in accelerating more efficient,secure and sustainabl

11、e ways of producing protein,this paper,Creating a Vibrant Food Innovation Ecosystem:How Israel Is Advancing Alternative Proteins across Sectors,has been developed by C4IR Israel(an independent member of the World Economic Forum Centre for the Fourth Industrial Revolution network),the Israel Innovati

12、on Authority and the Good Food Institute Israel.The paper highlights Israel as a case study for country-led approaches in which government leadership is creating the conditions for a robust,highly collaborative food-tech innovation environment focused on shared value a space that can produce scienti

13、fic breakthroughs,launch and support publicprivate sector partnerships and create a thriving bioeconomy.Country-led approaches have long been catalysts for transformative new technologies and innovation ecosystems that address our biggest challenges,improve our quality of life and benefit future gen

14、erations.Here again,by exploring and investing in alternative proteins,governments can play a leading role in ushering in a far brighter food future for all.Dror Bin Chief Executive Officer,Israel Innovation AuthoritySebastian Buckup Head of Network and Partnerships,Centre for the Fourth Industrial

15、Revolution;Member of the Executive Committee,World Economic ForumBruce Friedrich President and Founder,The Good Food InstituteCreating a Vibrant Food Innovation Ecosystem:How Israel Is Advancing Alternative Proteins Across SectorsMay 2024Creating a Vibrant Food Innovation Ecosystem 3PrefaceThe role

16、of emerging technologies and innovation as key enablers of food systems transformation cannot be understated.Coupled with the right investment and multistakeholder collaboration models,emerging technologies can support agrifood systems to become one of the worlds most hopeful responses to safeguard

17、nature,achieve climate action,improve food and nutrition security and reduce inequity.Recognizing that there is no silver bullet solution,the World Economic Forums Food Innovation Hubs Global Initiative and the Centre for the Fourth Industrial Revolution are working to build insights and develop fro

18、ntier thinking and new models of collaboration,in-country and globally,that can strengthen innovation ecosystems to capture the pace of technology for the benefit of the worlds food systems.Achieving universally accessible protein will require multiple transition pathways:4 1)accelerating protein di

19、versification;2)advancing sustainable production systems;and 3)driving consumer behaviour change.5 With the demand for protein expected to rise,a robust innovation ecosystem for protein pathways will play an enabling role in driving positive impact across intertwined agendas,including food,the envir

20、onment and nature,health and nutrition,livelihoods and economic growth.The vast breadth and reach of the protein sector calls for a complex system of solutions.A successful transition will rely on an appreciation of the trade-offs particular solutions will bring,recognizing both the losses and the g

21、ains and allowing for more challenging decision-making.It will also require actors to come together with a commonality of purpose,to accelerate action in support of achieving the necessary protein transitions.The future offers tremendous innovation potential for transition in the protein sector,and

22、technological advances present significant tools to make these protein transition pathways a reality.Written by the independent C4IR Israel,the Israel Innovation Authorityand the Good Food Institute Israel,this paper highlights one such solution pathway for alternate protein technologies and offers

23、insights into the building blocks for country-led innovation ecosystems.50%projected increase in global meat consumption by 2050(from 2012 levels).Creating a Vibrant Food Innovation Ecosystem 4Executive summaryNations around the world are becoming aware of the benefits of prioritizing alternative pr

24、oteins to meet their climate,biodiversity,food security and public health goals.This paper demonstrates the Israeli example of how government initiatives tailored to the ecosystems needs and challenges,and the countrys fundamental assets,form a resilient,cross-sector alternative protein ecosystem.By

25、 examining Israel as a case study,broader takeaways can be identified for other countries to follow,using local resources and highlighting the importance of international collaboration in this sector to shape the future of food.In recent years,there has been an unprecedented surge in public investme

26、nt and commitment to alternative protein research and development.Countries such as Australia,Brazil,Canada,China,Germany,India,Israel,Japan,the Netherlands,Singapore,the United Kingdom and the United States are recognizing the essential role that alternative proteins can play in future food technol

27、ogy,innovation and progress,complementing traditional production methods while bolstering the bioeconomy and highlighting the potential benefits for the environment and public health.There is a growing acknowledgement that,despite the industry being in its infancy,alternative proteins meat made from

28、 plants,cultivated from animal cells or fermentation-derived meat have transformative potential,particularly for farmers,who can benefit from and lead the transition towards a thriving alt-protein economy.Looking ahead to 2030,using agricultural side streams for alternative protein production presen

29、ts a significant opportunity to enhance sustainability and circularity within the food supply chain.In light of the escalating challenges posed by climate change and the need to ensure food security,nations are called on to undertake a collective effort to elevate alternative proteins as a solution.

30、Crafting a vision for this ecosystem requires a nuanced understanding of each countrys distinct attributes bilateral and multinational collaborations can play a crucial role in pooling strengths and overcoming shared challenges.Alternative proteins,due to their deep-tech nature,high capital expendit

31、ures(CAPEX)requirement and longer return on investment timelines,may pose investment challenges for some parts of the private sector.Governments which already allot billions of dollars each year to renewable energy and global health research and are also beginning to invest in better,safer,more effi

32、cient ways of producing meat can help alleviate this burden.They can do so by providing financial support,grants or incentives to facilitate scale-up efforts and attract institutional investors comfortable with long-term returns.In addition,proactive engagement in formulating clear regulations to en

33、sure product safety while encouraging innovation,drawing from the experiences of other nations,is essential.These interventions are effective in stimulating the sustainable growth of alternative proteins,positioning them as integral components of the future food landscape.External forecasts of the a

34、lternative protein market size by 2030 vary widely in their estimates from$58 billion6 to$570 billion7 but they all project robust growth from todays market size.Such market growth would demand unprecedented collaboration,investment and innovation in the sector.While there is a growing consensus tha

35、t the public sector must necessarily play a pivotal role8 in shaping this sectors trajectory,the specifics actions,funding and anticipated outcomes often remain undefined.Innovation at the scale needed cannot thrive in isolation;it requires the removal of barriers and the formation of a robust multi

36、sector,collaborative business environment.Paving the way for this sector to become a core industry needs a stronger and more coordinated effort than any entrepreneur or company can achieve independently.This white paper makes clear the essential role that governments play in propelling progress and

37、takes a detailed look at how one country is creating a collaborative and dynamic food-tech innovation ecosystem.It sheds light on how the Israeli governments Innovation Authority identifies strategic intervention points as it considers its own unique national resources,the inherent challenges,its pr

38、edominant status as an importer and the dynamics of the alternative protein value chain.By fostering a mutually beneficial partnership between the public sector and the rapidly evolving alternative protein business,the Israel Innovation Authority is paving the way for a smoother,quicker journey towa

39、rds innovation and sustainability a replicable approach other countries could adopt to boost the entire field and hasten global food systems transformation.Alternative proteins are game-changing agricultural innovations that,with proper levels of support,can help aid planetary and public health.Ther

40、e is a growing acknowledgement that alternative proteins have transformative potential,particularly for farmers.Creating a Vibrant Food Innovation Ecosystem 5The role of governments in advancing alternative proteins1Government leadership is needed to develop and promote alternative proteins and addr

41、ess one of the biggest global challenges of this era.1.Economic growth and innovationGovernments generally view the alternative protein sector as a source of future-resilient economic growth and job creation.They aim to promote a thriving environment of start-ups,businesses and research institutions

42、 by supporting research and development(R&D)and providing financial incentives.This enhances a countrys global competitiveness while stimulating new livelihoods,academiaindustry connections and economic vibrancy.According to 2023 analysis conducted by McKinsey economists for ClimateWorks Foundation

43、and the Global Methane Hub,alternative proteins are expected to support 83 million jobs9 globally,contributing to a sector projected to be worth nearly$700 billion by 2050.2.Food securityThe alternative protein sector is a strategic response to the increasing global demand for protein sources.In the

44、 face of population growth,climate change and resource scarcity,transitioning to alternative proteins reduces supply-chain risks,and diversifies and increases the efficiency of global food production.Investing in alternative proteins will also help make meat production more resilient10 to extreme we

45、ather,disease outbreaks and the emergence of crop diseases and pests(see Box 1).Countries that strategically adapt to evolving global food systems and diversify their food value chains stand to benefit from the positive impacts of integrating alternative proteins into their national policies.Israels

46、 proactive approach to fostering innovation in alternative proteins reflects our commitment to shaping a sustainable future for generations to come.By investing in academic research,as well as innovative start-ups at every stage and facilitating collaboration across industries,we are accelerating th

47、e growth of Israels alternative protein ecosystem.Positioned to drive sustainable and efficient solutions,Israel is poised to redefine the global landscape of alternative proteins technology and make an impactful change for a more resilient food future.Dror Bin,Chief Executive Officer,Israel Innovat

48、ion AuthoritySeveral motivating factors are at play in the field of alternative proteins,reflecting a broad recognition of the potential benefits and challenges associated with this transformative industry.Creating a Vibrant Food Innovation Ecosystem 6Alternative proteinsBOX 1Plant-based meatPlant-b

49、ased meat is produced directly from plants.Instead of relying on an animal to convert plants into meat or other animal-sourced foods,plant ingredients are turned directly into alternatives to meat and other protein-rich foods.Like animal-based foods,plant-based foods are composed of protein,fat,vita

50、mins,minerals and water.The new generation of plant-based foods looks,cooks and tastes like meat,eggs,dairy products and seafood.Cultivated meatCultivated meat is grown directly from animal cells instead of farm animals.Cultivating meat is similar to growing plants from cuttings in a greenhouse,whic

51、h provides warmth,fertile soil,water and nutrients.This new method of meat production enables the natural process of cell growth but in a more efficient environment.Cellular agriculture involves taking a small sample of cells from an animal and growing them in a cultivator.The cultivator facilitates

52、 the same biological process that happens inside an animal by providing the cells with the warmth and basic nutrients needed to transform them into meat:water,proteins,carbohydrates,fats,vitamins and minerals.The resulting cultivated meat beef,pork,chicken and seafood is identical to conventionally

53、produced meat at the cellular level,but made in a more sustainable way.FermentationAlternative protein companies are using fermentation in innovative ways to produce foods that deliver the distinctive flavours and textures of animal products without farming animals.Fermentation can be used to produc

54、e alternative proteins that look,cook and taste like meat through a process similar to the way in which foods such as tempeh are made.Precision fermentation uses yeast to produce real egg or dairy proteins(such as whey and casein),delivering familiar flavours and textures of foods like cheese and mi

55、lk without using animals.Source:GFI Israel,“Reimagining Meat”:gfi.org.ilPlant-based and cultivated meat require a small fraction of the land and cause far fewer emissions than industrial animal farming.Freed-up land can be repurposed for biodiversity preservation,reforestation and more ecologically

56、friendly and regenerative methods of animal farming.With such profound benefits for our environment,for food security and for global health,alternative proteins are one critical strategy in our work towards a food system that we can all be proud of.Bruce Friedrich,President and Founder,The Good Food

57、 Institute3.Environment and climate Food and agriculture account for one-third of global greenhouse gas(GHG)emissions.Animal agriculture alone including the crops and pastures to feed the animals accounts for between 11%and 20%of all GHG emissions.11,12 Conventional animal agriculture also faces sig

58、nificant limitations.Humanity is running out of room for food production,leading to the clearing of forests and the destruction of other ecosystems worldwide.A global shift towards alternative proteins is one solution,addressing the twin crises affecting climate and biodiversity by slashing agricult

59、ural GHG emissions,reversing deforestation and restoring critical ecosystems.According to the Boston Consulting Group,at 11%market penetration,alternative proteins would have the climate mitigation impact of almost totally decarbonizing air travel13 and this does not include the sequestration potent

60、ial of land freed up by decreased grazing and feed crop production.4.Technology leadershipGovernments worldwide have long been sponsors of research to strengthen innovative agricultural technologies.Being at the forefront of alternative protein innovation positions a country as a leader in emerging

61、technologies.Governments recognize the potential for global influence that comes with being a recognized hub for groundbreaking advances in food and agricultural progress and innovation.5.Regulatory frameworksWithin current frameworks,governments can create clear,supportive,agile and efficient regul

62、atory processes to ensure safe and transparent pathways that instil confidence in consumers and industry players alike,fostering a robust alternative protein market in a shift towards food systems that are more sustainable,secure and just.Animal agriculture alone including the crops and pastures to

63、feed the animals accounts for between 11%and 20%of all GHG emissions.Creating a Vibrant Food Innovation Ecosystem 76.Early adoption of innovationGovernments can drive society to become first movers in building a solid innovation ecosystem.They can encourage investment in holistic solutions that prov

64、ide the right conditions for innovation to occur,while also tackling the challenges of improving production systems and increasing customer acceptance,highlighting the importance of building on the full value chain and gaining insights at every step of the way when adopting new food-tech solutions.7

65、.Leveraging and enabling private investmentsWhen combined with private-sector investment,public investment has stimulated new markets,jobs and solutions.Privately funded research is valuable,but not sufficient;while private funding typically emphasizes applied science and commercialization to yield

66、swift returns for a small group of shareholders,public investments support long-term basic research,often resulting in unforeseen breakthroughs over extended time frames.14 Throughout history,from radar and information technology to clean energy and vaccines,the collaborative endeavours of public an

67、d private R&D have consistently demonstrated synergistic effects on scientific advancement,societal progress and economic growth.In addition,governments can actively de-risk15 new food-tech innovation,including in alternative proteins,for private investments.By making crucial resources and infrastru

68、cture accessible,governments provide the necessary foundation for businesses to thrive in this emerging sector.This involvement not only encourages greater private investments but also contributes to the sustainability and scalability of alternative protein ventures.8.Fostering academiaindustry coll

69、aborationsImplementing science,technology and innovation policies becomes integral to a governments overall strategy.Such policies contribute to a more inclusive,comprehensive and cohesive approach to R&D,ensuring that companies,consumers and the government can access the latest technologies at the

70、lowest possible cost.This,in turn,accelerates the development and adoption of alternative protein technologies,positioning nations at the forefront of food systems transformation.Driven by the motivations above,governments around the world are beginning to pay heed.But if the world is to reach its g

71、lobal climate,biodiversity,food security and public health goals,much higher levels of investment are needed to accelerate protein transitions at the scale and pace required.According to the Good Food Institutes 2022 State of Global Policy report,16 public support for the alternative protein ecosyst

72、em has likely surpassed$1 billion.Governments are increasing their financial,policy and regulatory support for alternative proteins but have yet to approach the annual support required to realize alternative proteins benefits to the economy,climate and global food systems.To unlock the full potentia

73、l of alternative proteins,it is estimated that$10 billion per year is needed in global public spending17 on R&D and commercialization.As an investment,alternative proteins have already attracted billions in private funding(for cultivated,plant-based and fermentation-based meat).But this is not nearl

74、y enough.For cultivated meat specifically,less than$3 billion in capital has been invested,spread across just over 100 companies.That is not even the cost of one battery factory for electric vehicles and is a tiny fraction of the$1.7 trillion invested in clean energy in 2023.18 Currently,cultivated

75、meat technologies are at a nascent stage of development but have the potential to scale and attract investment similar to other clean-tech investments.The investment needed to advance food tech is substantial,posing a challenge for many countries with limited financial resources.Recognizing the vary

76、ing capacities of nations and the different roles each country can have in the alternative protein value chain,strategic partnerships become imperative to ensure shared investments,expertise and technological advances.Collaborative efforts can bridge financial gaps and support inclusive growth,promo

77、ting a global landscape in which all nations can actively participate in shaping a sustainable and resilient future through alternative proteins.Global forums such as the Food Innovation Hub19 could significantly address common anticipated challenges,such as ensuring consumer acceptance and creating

78、 a level playing field alongside the traditional meat industry.Governments need to consider investing in open-access research and creating private-sector incentives to realize the full economic and societal benefits of plant-based and cultivated meat and make these options accessible to all.Specific

79、ally,governments should consider funding science,creating scientific innovation centres and incentivizing private-sector R&D,manufacturing and infrastructure expansion focused on alternative meat production.Investment tax credits,loan guarantees and other forms of financial support,as well as demons

80、tration projects,have stimulated explosive growth in the renewable energy and electric vehicle(EV)sectors and can stimulate similar progress for alternative protein infrastructure.Federally supported innovation,in the form of increased investment in alternative protein R&D,can have a multiplier effe

81、ct,leading to a more resilient food supply,more choices for consumers,climate-forward and agricultural job creation,nature-positive protein production and a stronger global bioeconomy.Less than$3 billion in capital has been invested in cultivated meat not even the cost of one battery factory for ele

82、ctric vehicles.Creating a Vibrant Food Innovation Ecosystem 8Understanding the present challenges in the field2Through thoughtful,targeted and strategic interventions,governments can effectively address the diversity of challenges faced by the alternative protein sector.1.Cost competitivenessThe alt

83、ernative protein sectors capital expenditures(CAPEX)pose a challenge for the continued research and development needed to optimize production processes.Given the deep-tech nature of alternative protein innovation,substantial investment is essential to expand production capabilities and meet the incr

84、easing demand.20 Scale-up efforts will require investment in long-operation infrastructure,necessitating institutional investors comfortable with long-term returns.21 Governments can contribute by providing financial support,grants or incentives to alleviate the financial burden on companies to scal

85、e up their operations.2.Regulatory uncertaintyThe alternative protein sector operates within a dynamic and evolving technological landscape.Yet lessons from countries such as Israel,Singapore and the US indicate that existing regulatory frameworks can effectively accommodate the unique characteristi

86、cs of these innovations.While proactive engagement from governments is essential in formulating clear regulations to ensure product safety and encourage innovation,there is also a need to learn from the experiences of other nations in this domain.3.Collaboration with local industriesCollaboration is

87、 crucial among food-tech start-ups,farmers,food industries and pharmaceuticals as these sectors often possess the requisite expertise in scaling up and large-scale production.Governments can facilitate strategic partnerships,providing a platform for knowledge exchange,technology transfer and collabo

88、rative initiatives that use existing know-how within these industries.By encouraging and supporting collaboration,governments contribute to accelerating alternative protein production capabilities,ultimately fortifying the sectors position in the global market.22Through adopting a comprehensive appr

89、oach encompassing financial support,regulatory clarity and industry collaboration,governments can drive the sustainable growth of alternative proteins,positioning them as vital components of the future food landscape.Governments play a pivotal role in supporting and advancing deep-tech sectors such

90、as alternative proteins.Through strategic public investments in research,infrastructure and regulatory frameworks,governments can lay the foundation for private-sector involvement and drive transformative change in the global food systems while benefiting from new economic opportunities.Adi Ben Tov,

91、Associate Director of Policy,The Good Food Institute IsraelGovernments are well positioned to address the current challenges within the global alternative protein sector.Such support will help the entire industry grow and ensure successful integration into the mainstream food market.Creating a Vibra

92、nt Food Innovation Ecosystem 9Global acceleration of public support for alternative proteins3In many countries,government support for research into alternative proteins is taking off,but more funds are needed to enable the sector to grow at the necessary pace.In addition to making notable investment

93、s in alternative protein R&D and commercialization,governments around the world are incorporating sustainable proteins into their bioeconomy,biomanufacturing,food security,global health and sustainability strategies.However,to accelerate protein transitions at the scale and pace required,much greate

94、r levels of investment are needed.The following section outlines examples of three countries engaging with this challenge.DenmarkDenmark has spearheaded a groundbreaking strategy for a plant-powered future by investing more than 100 million in the Fund for Plant-Based Foods.This comprehensive action

95、 plan has many components,including bonuses to Danish farmers who grow plant-based protein crops for human consumption,professional education and initiatives relating to export activities,production and processing and robust research and development.Denmarks strategic approach23 reflects a commitmen

96、t to promoting sustainability and innovation across the alternative protein landscape.SingaporeThe Singaporean government has targeted investments in alternative proteins,24 anticipating the future demand for sustainable protein sources.The Food Tech Innovation Centre(FTIC),a partnership between Nur

97、asa and the Agency for Science,Technology and Research(A*STAR)Singapore,offers R&D and advisory services,lab-to pilot-scale facilities and potential investment support.Singapore was also the first country to approve the sale of cultivated meat,setting a precedent.The NetherlandsIn 2020,the Dutch Min

98、istry of Agriculture,Nature and Food Quality introduced the Dutch National Protein Strategy,25 outlining ambitious goals to enhance self-sufficiency in plant-based and innovative proteins over the next five to ten years.The Netherlands,facing an 80%dependency on vegetable protein imports and holding

99、 the title of the largest soybean importer in the European Union,is actively translating this policy into action and in doing so is reshaping the nations protein landscape.When it comes to alternative proteins,the importance of global collaborations cannot be overstated.Genuine progress necessitates

100、 a unified global effort.By combining resources,knowledge and innovation globally,we can expedite the adoption of sustainable protein sources and effectively address pressing issues such as food security and environmentalsustainability.Shani Dayan,Project and Partnership Manager,Israeli Center for t

101、he Fourth Industrial Revolution(C4IR),Israel InnovationAuthorityCreating a Vibrant Food Innovation Ecosystem 10Case study:How Israel is advancing alternative proteins across sectors4In Israel,entrepreneurs,academics and the public sector are combining to drive the emergence of the alternative protei

102、n industry.4.1 The Israeli alternative protein ecosystem todayIsraels leadership in alternative proteins is a testament to the Innovation Authoritys commitment to innovation and disruption in the food industry.Over 75%of the Authoritys investments in food technologies are directed towards high-risk

103、deep technologies.We enable the development of growth verticals like food incubators and collaborative consortiums such as the Cultivated Meat Consortium,as well as direct funding of companies,from early-stage start-ups all the way to mature companies with production lines.Leveraging multidisciplina

104、ry research,an entrepreneurial ecosystem and a proven track record in agriculture,biotechnology and engineering,Israel stands at the forefront of disruptive innovation in the food industry.Ronit Eshel,Senior Director,Head of Climate-Tech and Food-Tech Sector,Israel Innovation AuthorityThe Israeli al

105、ternative protein landscape has experienced a significant transformation of leadership over the past five years,driven by an effective blend of multidisciplinary academic knowledge,a dynamic and risk-taking entrepreneurial environment and active involvement from the public sector.These have laid the

106、 groundwork for the sectors further growth and development in the country.Fostering a collaborative academic landscape:The actively collaborative ecosystem of entrepreneurs,researchers,food companies and the public sector in Israel creates an environment that is conducive to the development and adva

107、nce of alternative protein technologies.More than 70 researchers are working on alternative protein research,10 of whom embarked on their research journey in 2023,contributing to the developing landscape of this nascent and evolving sector in 2023.Moreover,there are almost 300 researchers working in

108、 adjacent areas,such as biotechnology,microbiology and pharmaceuticals,with the know-how and expertise that could contribute to the growing alternative protein industry.The Hebrew University and the Technion(Israel Institute of Technology)both declared in 2023 that they will establish research centr

109、es dedicated to food systems and alternative proteins.This move is expected to boost the local research and business environment significantly.Creating a Vibrant Food Innovation Ecosystem 11Alternative protein research in Israels major academic institutionsStart-ups in Israels alternative protein se

110、ctorFIGURE 1FIGURE 2CultivatedPlant-basedFermentationVolcani Center(ARO)Hebrew UniversityTechnionMigalTel-Aviv UniversityIsrael Oceanographic and Limnological ResearchWeizmann InstituteBar Ilan UniversityAshkelon Academic CollegeTel-Hai CollegeThe Open University of IsraelBen-Gurion UniversityTriang

111、le Research and Development Center024681012Number of projectsAcademic institutionsFermentation(19)Cultivated(20)Seed(32)Development(14)Pilot and scale-up(12)Commercialization and growth(15)Plant-based(34)Source:GFI Israel,2024Source:GFI Israel,2024Ensuring progressive and evolving venture creation:T

112、here was a record high of 15 new start-ups in Israels alternative protein sector in 2023.These diverse ventures include start-ups in all three technologies(cultivated,plant-based and fermentation-based meats),along with companies focusing on final products,ingredients and supporting technologies.Thi

113、s diversity allows for synergies and further development of the field.As of January 2024,Israel has 73 active start-ups in this sector alone and more than 200 start-ups in food technologies as a whole.Creating a Vibrant Food Innovation Ecosystem 12Establishing a key investment destination:Israel occ

114、upies the second position globally in alternative protein investment over the past half-decade,trailing only the United States.In 2022,25%of private investments in cultivated meat were invested in Israeli companies.Developing a beta site for alternative protein product launch:The characteristics of

115、the local market drive the development of alternative proteins.A high percentage of vegan and kosher-adhering customers combines with a general willingness to embrace and financially support new,innovative and premium food products.As the market is small,and food exports are limited,Israels local fo

116、od industry views innovation as a considerable growth engine,and actively engages with and supports the in-country alternative protein ecosystem.Israel was the first country in the world to approve cultivated beef,26 with the approval of Aleph Farms whole cuts,and was the third globally to approve a

117、 cultivated meat product.The local business environment allows the Israeli regulator to adapt to rapid technological change and advance the country in the global race for alternative proteins.Global investment in alternative proteins by country in$millions(20142023)FIGURE 3$200M$400M$600M$800M$1B$1.

118、2BCountryUnited StatesIsraelSwedenUnited KingdomChileAustraliaFranceSingaporeNetherlandsChina0$10.2B$1.2B$435M$332M$315M$308M$263M$214MSum of deal amount($)$767M$570MSource:Net Zero Insights,2023The global food systems face immense challenges,from failures in the global food supply chain to macroeco

119、nomic declines and geopolitical tensions that underscore the need for transformative solutions.Achieving net-zero emissions and building resilient food systems necessitate the widespread adoption of innovative alternative protein technologies,and the Israeli ecosystem is paving the way.Developing a

120、national strategy is the key to making a more impactful use of every public investment.Nir Goldstein,Chief Executive Officer,The Good Food Institute IsraelCreating a Vibrant Food Innovation Ecosystem 134.2 Elevating alternative proteins as a national priority for sustainable growthPrioritizing R&D:T

121、o harness and maximize innovation in the alternative protein sector,the Israeli government,following a recommendation by the Israeli National Council for Research and Development,has designated alternative proteins among the nations top five priority R&D areas.27 The selection criteria,determined by

122、 the council,evaluated factors such as Israels comparative advantages in certain sectors,its strategic needs as a country,its strength in R&D and its position as a global innovation hub,and whether the specific sector needs government support and has a scientific component.Additional criteria includ

123、e the potential national security element,the diversity of human capital and talent development,and the possibilities for cross-sector collaboration.Embedding economic levers:Strategic research,recently begun by the Israel Innovation Authority with the Good Food Institute Israel(GFI Israel)and Shald

124、or strategy consulting firm,has recognized that implementing a well-structured national support strategy could enable the local alternative protein sector to play a pivotal role in shaping the domestic business ecosystem by 2030.There could be significant growth in the number of companies,resulting

125、in more than 200 companies and more than a dozen manufacturing facilities being established in Israel.Job opportunities would flourish,with an estimated 10,000 positions,including one-third in manufacturing roles.From an economic perspective,a substantial contribution of about$2.5 billion to the loc

126、al economy is anticipated,encompassing exports,local wages,corporate taxes and more.Mapping the alternative protein value chain:Israels prominence in alternative proteins,the potential economic benefits,its international positioning(i.e.its perception and reputation on the world stage,especially in

127、relation to its leadership in technology and innovation)and the opportunities for global collaboration have served as the foundation for the government to adopt a proactive and holistic perspective on the alternative protein business environment.Companies in different industries require tailored sup

128、port to meet varying challenges throughout their journey.Therefore,viewing the business environment specific to the alternative protein value chain allows a more exhaustive and coherent study of conditions,existing unmet needs,potential support and the roles of the private sector and government.The

129、strategic research mentioned above mapped the seven main stages in the alternative protein value chain that companies in the alternative proteins industry go through from R&D to scale,and studied the current state of companies and researchers,their unmet market needs,areas that could be further ampl

130、ified and the potential courses of action to address each.Stages in the development,manufacturing and marketing of an alternative proteins food productFIGURE 4R&DBasic researchApplied researchInitialventurePilot stageInitial productionCommercial productionMarketing and distributionSource:Shaldor Str

131、ategic ConsultingCreating a Vibrant Food Innovation Ecosystem 14In establishing a cohesive national strategy for alternative proteins,the benefits extend far beyond mere government support.It serves to unify the ecosystem,empowering stakeholders to speak a common language and collaborate effectively

132、 on shared challenges,thereby driving impactful change.Alla Voldman-Rantzer,Vice-President Strategy and Policy,The Good Food Institute IsraelRecognizing the nations intrinsic constraints:Even with these attributes,there are inherent limitations.Among them is identifying local supply-chain gaps.The I

133、sraeli alternative proteins industry faces challenges arising from the relatively small and geographically constrained local market.These factors pose obstacles to widespread industry adoption,necessitating tailored interventions.Additionally,budget constraints,especially when compared to larger eco

134、nomies such as the US and China,and the absence of major food and pharmaceutical conglomerates in the local market further limit the support available.Bilateral and multilateral cooperation among countries with different advantages along the supply chain may help overcome these constraints one examp

135、le is the collaboration between the US and Israel through the BIRD Foundation,28 which facilitates connections and funds cooperation between Israeli start-ups,which provide technology,and US companies,which offer production capacities.Cooperation between the Israeli alternative protein industry and

136、international partnersFIGURE 5Early adopters marketHigh share of vegansWillingness to experiment with new productsHigh pricingEntrepreneurship and venture capitalEntrepreneurship in a variety of sectorsDeveloped venture capital ecosystemRisk-taking culturePublic sector involvedGroundbreaking science

137、 and technologyWorld-leading faculties and researchers in food engineering and related fieldsFood industry giantsMarketing and operations Boost research investments,services Synergy with existing industriesOther industries(pharma,chemicals,food)Infrastructure and human capital Market sizeCommercial

138、potentialEase of distributionClose to R&D facilityBudgetsStart-upsAcademiaIndustry and factory buildingSource:Shaldor Strategic Consulting15Creating a Vibrant Food Innovation Ecosystem 4.3 Government intervention pointsIdentifying the elements necessary for a robust alternative protein industry and

139、recognizing market constraints both inform government support,enabling focused intervention to stimulate innovation and growth.Through the Israel Innovation Authority,the government is developing a comprehensive approach to investing in the business environment at various stages and with multiple st

140、akeholders.A thorough examination of the value chain facilitates a nuanced understanding of unmet needs,the potential support mechanisms and critical leverage points at which government intervention can have maximum impact.Stages of research and developmentFIGURE 6R&DBasic researchApplied researchIn

141、itialventurePilot stageInitial productionSource:Shaldor Strategic ConsultingDeepening the roots with basic research:The alternative protein industry,deeply grounded in agriculture,biology and medicine,requires advanced infrastructure and skilled personnel for it to progress,with government support i

142、n establishing research and development foundations29 imperative to develop the science.In 2022,GFI Israel together with the Israeli Ministry of Agriculture and the Ministry of Innovation,Science and Technology published an open call to fund research grants of$1.2 million total and up to$85,000 per

143、project in alternative proteins.Of the 25 proposals submitted,the top 15 received a grant.In 2023,the call for proposals was published for the second time.Out of the 70 active researchers,48 received funding from GFI.Cultivating applied research:Applied research focuses on the technological developm

144、ent of alternative protein sources,processes and product formulations.This stage establishes intellectual property and is the foundation for forming companies within the business environment.Investing$18 million over three years,the Israel Innovation Authority formed the Cultivated Meat Technologica

145、l Consortium,comprising 14 companies and 10 academic laboratories,partnering to develop technologies for the cost-effective production of cultivated meat.30 Incubating innovation at the initial stages:The initial stage involves incubating start-ups through laboratory-scale research and development.T

146、he emphasis is on developing a product with commercial potential based on applied research,focusing on validating proof of concept.This phase varies widely among technology types and can span several years.The Israel Innovation Authority supports two large food-tech incubators:Strauss Groups The Kit

147、chen and Tnuvas Fresh Start.These are responsible for establishing more than 25%of all alternative protein start-ups.The incubators offer Creating a Vibrant Food Innovation Ecosystem 16a complete umbrella for start-ups,including shared workspaces,lab equipment,investor access,R&D assistance and fina

148、ncial investment.Scaling up at the pilot stage:In the pilot stage,companies develop the production process,before transitioning towards larger operations.Scaling up requires more extensive equipment and infrastructure,often housed in a dedicated“pilot plant”.Contract development and manufacturing or

149、ganizations(CDMOs)that in biotech traditionally serve pharmaceutical companies have begun to expand to the cultivated meat industry.In Israel,YDLabs fermentation centre a CDMO specializing in process development and optimization(volume ranging from a few litres at lab scale to 1,000 litres for proce

150、ss development)provides testing,R&D support,economic feasibility experiments,consumer testing and guidance on food regulations.In 2023,YDLabs won Israel Innovation Authoritys$13.5 million tender for fermentation services of up to 20,000 litres,spanning initial manufacturing.31The selection of YDLabs

151、 by the Israel Innovation Authority as a precision fermentation service provider marks a pivotal step in facilitating the transition from R&D to pilot stage infrastructure within the alternative protein market.This initiative not only enables local and global companies to conduct crucial development

152、al testing of novel foods in Israel but also establishes a centre of excellence that promises quality and reliability in service provision.By fostering critical infrastructures in the ecosystem,we aim to bolster alternative protein initiatives globally,ensuring that innovative solutions thrive and a

153、ddress pressing global challenges.Noa Matarasso,Senior Director,Academia/Infrastructure Division,Israel Innovation AuthorityNavigating initial production:At the semi-industrial scale,companies test scalability and explore commercialization potential through collaborations.Choices at this stage range

154、 from building proprietary facilities to partnering with existing manufacturers,using co-working facilities or opting for a contract manufacturing organization(CMO)or CDMO.A special track for“Development to Production R&D”was launched three years ago by the Israel Innovation Authority,funding the de

155、velopment of manufacturing processes and investing in companies while they transition from lab to production.The authority invested in three companies in 2023 on that path.Rabobank,a Dutch bank specializing in food and agriculture companies,provides them with specialized financial services,such as l

156、ow-rate loans and credit lines,especially for establishing production facilities.4.4 A global perspective on the value chainEmbracing a holistic view of global food systems enables Israel to identify its unique contributions and focus areas within the alternative proteins ecosystem.Understanding eac

157、h country and geographys distinctive role facilitates collaborative efforts,enhancing the collective impact on the industrys evolution.The Israeli governments strategic involvement across the local alternative proteins value chain reflects a nuanced understanding of the challenges and opportunities,

158、setting the stage for sustained innovation and growth within this dynamic ecosystem.Alternative proteins offer a globally scalable regional food solution produced by both multinational companies and small-scale farmers with indigenous crops adapted to local climates and suited to the needs and taste

159、s of local communities.Like the ecological dynamics within natural ecosystems in which diversity equals resilience diverse people,crops,models and solutions will be needed to infuse much-needed resilience into variable global food systems.Creating a Vibrant Food Innovation Ecosystem 17ConclusionGlob

160、al attention is increasingly turning to alternative proteins as essential components in the future of biotechnology,a shift underscored by policy developments,with key players such as the US Department of Defense32 and Department of Energy33 emphasizing the importance of alternative proteins in shap

161、ing the biotech landscape.China has unveiled a five-year plan to bolster its bioeconomy,with a focus on alternative protein.34 A first-of-its-kind report from the United Nations Environment Programme35 focused 100%on alternative proteins emphasized how transitioning towards plant-based,cultivated an

162、d fermentation-derived meat can benefit the environment and public health.Farmers stand to benefit from the transition towards a thriving alt-protein economy,as alternative proteins reduce climate change impact risks,diversify income streams,help rebuild and retain soil,soak up carbon,improve water

163、quality and infuse much-needed crop diversity and resilience into global food systems.36 Looking ahead to 2030,the world will likely witness major changes in energy,agriculture,industry and food systems as major drivers for addressing climate challenges.Projections indicate a substantial surplus of

164、agricultural side streams,particularly from corn,soy,wheat,sugarcane,barley,rice,canola and tomatoes.Using these for alternative protein production represents a significant opportunity to enhance sustainability and circularity within the food supply chain,optimizing resource use and creating a more

165、resilient agricultural sector.Additional evidence and research are needed to tap into the potential for a diversified agriculture sector.It is imperative that nations see alternative proteins as a solution pathway.Embracing the transformative potential of alternative proteins requires a collective a

166、nd concerted effort on the global stage.Nonetheless,this is an industry in its infancy and the challenges that surface as it grows need to be addressed through breakthrough technologies,knowledge and leadership.Escalating challenges posed by climate change and environmental degradation,and the imper

167、ative to enhance food security,mean the pivotal role of alternative proteins in revolutionizing food systems cannot be overstated.Creating a Vibrant Food Innovation Ecosystem 18In forging a global alternative protein ecosystem,Israels leadership,in collaboration with the C4IR network,holds the key t

168、o making a profound global impact.The strategic actions of both entities set the blueprint for cross-sector collaboration as well as pave the way for transformative change on a global scale.By adopting this approach,nations can catalyse innovation,enhance food sustainability and address pressing cha

169、llenges,ushering in a future where the alternative protein sector makes a lasting positive impact on both the environment and public health.Daniella Partem,Head,Israeli Center for the Fourth Industrial Revolution(C4IR),Israel Innovation AuthorityCrafting a vision for an alternative protein ecosystem

170、 calls for a nuanced understanding of the unique characteristics,challenges and market dynamics that each country brings to the table.Far from a one-size-fits-all approach,this requires a thoughtful strategy aligned with each nations distinct attributes and assets.Leveraging the diverse capabilities

171、,infrastructure and expertise inherent in different countries becomes a cornerstone for the success of the alternative protein sector.Bilateral and multinational collaboration including joint research,development and harmonization of standards and international support are powerful instruments for c

172、reating a global network of expertise and resources.The benefit of these global bridges lies in recognizing and harnessing the synergies that arise from diverse perspectives.Each countrys unique characteristics whether its agricultural strengths,technological prowess or consumer preferences contribu

173、te valuable pieces to the global alternative protein puzzle.In collaborative endeavours,countries pool their strengths,address shared challenges and collectively contribute to overcoming barriers in the alternative proteins landscape.Such collaborations extend beyond geographical boundaries and esta

174、blish a framework for the seamless exchange of knowledge,technology and best practices.By expanding participation in these initiatives,more countries can join forces to work towards achieving the$10 billion investment target,ensuring that research,development and commercialization efforts are suffic

175、iently funded to realize the full potential of protein diversification and ensure global food security.Creating a Vibrant Food Innovation Ecosystem 19Israel Innovation Authority Shai AgamiHead of Policy and AdvocacyYair BezmanFood Tech Evaluator and Content ExpertHanan BrandVice-President,Head of St

176、artup Division Sagi DaganVice-President,Head of the Strategy DivisionOrit Efrimi Senior Director Of Operations and PurchasingShlomi Kofman Vice-President and Head of International Collaborations DivisionNoa MatarassoSenior Director,Academia/Infrastructure DivisionMichal ReisfeldChief Marketing Offic

177、erZachi Schnarch Deputy Chief Executive Officer,Head of Technological DivisionTomer SegalovichChief of StaffHagit Sela-LidorInternational Marketing ManagerAviv Zeevi BalasianoVice-President,Head of Technology Infrastructure DivisionThe Good Food InstituteNir Goldstein Chief Executive Officer,GFI Isr

178、aelContributorsAcknowledgementsThe Good Food InstituteAdi Ben TovAssociate Director of Policy,GFI IsraelSheila VossSenior Vice-President,Communications,GFI Alla Voldman-RantzerVice-President,Strategy&Policy,GFI IsraelIsrael Innovation Authority Shani DayanProject and Partnership Manager,Israeli Cent

179、er for the Fourth Industrial Revolution(C4IR),Israel Innovation AuthorityRonit EshelSenior Director,Head of Climate-Tech and Food-Tech Sector,Israel Innovation AuthorityDaniella PartemHead,Israeli Center for the Fourth Industrial Revolution(C4IR),Israel Innovation AuthorityLead AuthorsCreating a Vib

180、rant Food Innovation Ecosystem 20Shaldor Strategic Management ConsultingMaor KoltTeam LeaderPorat PeretzConsultant Omer TeperManaging DirectorIsraeli Prime Ministers OfficeTal Gilboa Advisor to the Prime Minister on Animal RightsDaniel IttahSenior Team Manager,Economy and InfrastructureC4IR Israel i

181、s a member of the World Economic Forum Centre for the Fourth Industrial Revolution and works closely with the Centre for Nature and Climate.About C4IR Israel:Facilitated by the Israel Innovation Authority,the Centre drives innovative technology initiatives locally and globally.Through multistakehold

182、er engagement,ecosystem promotion and cross-sector collaborations,it fosters knowledge sharing and advances groundbreaking solutions involving governments,corporations and experts worldwide.About the World Economic Forums Centre for the Fourth Industrial Revolution:As the future-oriented global plat

183、form for multistakeholder dialogue and cooperation,the C4IR is exploring exponential technologies and driving responsible adoption and application,leveraging a global network of 19 independent national and thematic centres.Creating a Vibrant Food Innovation Ecosystem 21Endnotes1.United Nations,“Stri

184、ving to Feed 10 Billion People in 2050”:https:/www.un.org/en/academic-impact/striving-feed-10-billion-people-2050.2.Michael A.Clark et al.,“Global Food System Emissions Could Preclude Achieving the 1.5 and 2C Climate Change Targets”,Science 370,2020,pp.705708:https:/www.science.org/doi/full/10.1126/

185、science.aba7357.3.Food and Agriculture Organization of the United Nations,The Future of Food and Agriculture:Alternative Pathways to 2050:Supplementary Material,2018,p.64:https:/www.fao.org/3/CA1564EN/CA1564EN.pdf.4.World Economic Forum,Meat:The Future A Roadmap for Delivering 21st-Century Protein,2

186、019:https:/www3.weforum.org/docs/WEF_White_Paper_Roadmap_Protein.pdf.5.Ibid.6.Credit Suisse Research Institute,The Global Food System:Identifying Sustainable Solutions,2021:https:/www.credit- Kearney,How Will Cultured Meat and Meat Alternatives Disrupt the Agricultural and Food Industry?,2019:https:

187、/ Nations Environment Programme,Whats Cooking?An Assessment of Potential Impacts of Selected Novel Alternatives to Conventional Animal Products,2023:https:/www.unep.org/resources/whats-cooking-assessment-potential-impacts-selected-novel-alternatives-conventional.9.ClimateWorks Foundation,“Reducing M

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191、ech”,TIME,2022:https:/ Food Institute,The State of Global Policy on Alternative Proteins,2023:https:/gfi.org/resource/alternative-proteins-state-of-global-policy/.17.Global Innovation Needs Assessments(GINAs),“Protein Diversity”,2021:https:/www.climateworks.org/wp-content/uploads/2021/11/GINAs-Prote

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196、023:https:/gfi.org/resource/alternative-proteins-state-of-global-policy/.24.Vegconomist,“Singapore Recruits Alt Protein Scientists amid Rising Food Security Concerns”,2023:https:/ a Vibrant Food Innovation Ecosystem 2225.United States Department of Agriculture,“Dutch Ministry of Agriculture Launches

197、 National Protein Strategy”,2021:https:/apps.fas.usda.gov/newgainapi/api/Report/DownloadReportByFileName?fileName=Dutch%20Ministry%20of%20Agriculture%20Launches%20National%20Protein%20Strategy%20_The%20Hague_Netherlands_01-09-2021.26.Government of Israel Ministry of Foreign Affairs,“Israel Approves

198、Regulatory Measures for the Production of Beef without Using Animals”,2024:https:/www.gov.il/en/departments/news/regulatory-measures-approved-for-the-production-of-beef-without-using-animals-17-jan-2024.27.Government of Israel Ministry of Foreign Affairs,“Ministry of Innovation Determines Israels Na

199、tional R&D Priorities”,2022:https:/www.gov.il/en/departments/news/ministry-of-innovation-determines-israel-s-national-r-d-priorities-9-sep-2022.28.Bird Foundation:https:/ Lipsis et al.,“Macroeconomic Effects of Public R&D”,UCL,2023:https:/www.ucl.ac.uk/bartlett/public-purpose/sites/bartlett_public_p

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201、409595.31.Israel Innovation Authority,“YDLabs to Establish Microorganism Fermentation Labs for the Foodtech Industry”,2023:https:/innovationisrael.org.il/en/press_release/ydlabs-to-establish-microorganism-fermentation-labs-for-the-foodtech-industry/.32.US Department of Defense,“DOD Launches Distribu

202、ted Bioindustrial Manufacturing Program to Bolster Domestic Supply Chain”,2024:https:/www.defense.gov/News/Releases/Release/Article/3662704/dod-launches-distributed-bioindustrial-manufacturing-program-to-bolster-domesti/.33.US Department of Energy,“FY24 Energy and Emissions Intensive Industries FOA”

203、,2024:https:/go.gfi.org/e/667193/47-9e80-4977-a47d-dcfd554d35cc/7tbl2v/846908581/h/cGDDR_4kJ32VdVz_BMsx6pQ7loPl48KGyURcT9joUJE.34.X.Zhang et al.,“The Roadmap of Bioeconomy in China”,National Library of Medicine,US Government National Library of Medicine,2022:https:/www.ncbi.nlm.nih.gov/pmc/articles/

204、PMC9995158/#:text=DEVELOPMENT%20GOALS%20OF%20CHINESE%20BIOECONOMY&text=According%20to%20the%20plan%2C%20China,I%3A%20(20212025).35.United Nations Environment Programme,Whats Cooking?An Assessment of Potential Impacts of Selected Novel Alternatives to Conventional Animal Products,2023:https:/www.unep

205、.org/resources/whats-cooking-assessment-potential-impacts-selected-novel-alternatives-conventional.36.Purdue University,“Soybean Industry to Benefit from Growing Demand of Cell-Cultured Meat”,2023:https:/www.purdue.edu/newsroom/releases/2023/Q3/soybean-industry-to-benefit-from-growing-demand-of-cell

206、-cultured-meat.html.Creating a Vibrant Food Innovation Ecosystem 23World Economic Forum9193 route de la CapiteCH-1223 Cologny/GenevaSwitzerland Tel.:+41(0)22 869 1212Fax:+41(0)22 786 2744contactweforum.orgwww.weforum.orgThe World Economic Forum,committed to improving the state of the world,is the International Organization for Public-Private Cooperation.The Forum engages the foremost political,business and other leaders of society to shape global,regional and industry agendas.